Cancer drugs linked to severe chronic peripheral nerve pain for 4 in every 10 patients

Platinum based drugs, taxanes, and lung cancer associated with highest pain prevalence Worldwide, cancer chemotherapy is linked to persistent severe peripheral nerve pain (neuropathy) for around 4 in every 10 patients treated with these drugs, suggests a pooled data analysis of the available evidence, published in the open access journal Regional ...

Likely 50-fold rise in prevalence of gender related distress from 2011-21 in England

But condition still uncommon, affecting fewer than 1 in 200 17-18 year olds, figures suggest Levels of anxiety, depression, and self-harm are high among recorded cases Accessing timely care live issue for young people and their families, second study shows The prevalence of psychological distress caused by a mismatch between ...

Major uncertainties remain about impact of treatment for gender related distress

Syntheses of available evidence suggest it’s impossible to determine pros or cons Findings on puberty blockers and gender affirming therapy back those of Cass Review Major uncertainties remain about the impact of puberty blockers and gender affirming hormone therapy on children and young people with gender related distress (gender dysphoria), ...

Exercise and improved diet before surgery linked to fewer complications and enhanced recovery

Results show potentially meaningful effects, but are generally of low certainty Actively preparing for major surgery by exercising and improving diet (known as “prehabilitation”) is associated with fewer complications, less time in hospital, and improved recovery and quality of life in adults, finds an analysis of clinical trials published by The ...

2025-01-23T10:58:59+00:0023 January 2025|Press release, The BMJ|

SGLT-2 drug plus moderate calorie restriction achieves higher diabetes remission

Study provides a practical strategy to achieve remission for adults with type 2 diabetes Adults with overweight or obesity and type 2 diabetes who are given the sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin alongside moderate calorie restriction achieve much higher rates of remission compared with calorie restriction alone, ...

2025-01-23T10:56:30+00:0023 January 2025|Press release, The BMJ|

Muscular strength and good physical fitness linked to lower risk of death in people with cancer

Tailored exercise may prolong life in these patients, suggest researchers Muscular strength and good physical fitness are linked to a significantly lower risk of death from any cause in people with cancer, finds a pooled data analysis of the available evidence, published online in the British Journal of Sports Medicine. Tailored ...

Childhood poverty and/or parental mental illness may double teens’ risk of violence and police contact

These kids more likely to carry/use weapons and get on wrong side of the law by age of 17 Factors may explain nearly third of UK teen weapon issues + quarter of police contact cases Living with persistent poverty and/or parental mental illness throughout childhood may double the risk of ...

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