May be time to reassess use of PARP inhibitor drugs in these patients, say researchers Findings pave way for refining genetic testing and personalised treatment in prostate cancer Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate ...
First trial to show feasibility of gene signature to tailor treatment for high risk patients Using a gene signature technique to tailor chemotherapy for patients with early triple negative breast cancer shows promise as a way to improve disease-free survival, finds a clinical trial published by The BMJ today. Triple negative breast ...
Proportion much higher than that assessed with widely used measure (BMI) Real impact of obesity on risk has likely been underestimated, say researchers Around 40% of postmenopausal hormone positive breast cancer cases may be linked to excess body fat, suggests Spanish research published online in the Journal of Epidemiology & Community ...
It complements traditional pain relief and broadens repertoire of options, say researchers Twenty minutes of mindful breathing, which focuses a person’s attention on their breath, can rapidly reduce the intensity and unpleasantness of cancer pain and relieve the associated anxiety, suggest the findings of a small comparative study, published online ...
Results are, overall, positive and reassuring, but further work is needed to address rise in some less common types of cancer, say experts Cases of cancer among UK men and women aged 35-69 years have seen a modest rise over the last quarter of a century, but there has also ...
Particularly those approved through “fast track” pathways Many cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved through expedited (“fast track”) pathways, finds a study published by The BMJ today. And despite pharmaceutical industry claims that high drug prices are ...
Encourage men to improve fitness to help lower risk of getting the disease, say researchers An increase in annual cardiorespiratory fitness by 3% or more is linked to a 35% lower risk of developing, although not dying from, prostate cancer, suggests research published online in the British Journal of Sports Medicine. ...
Increased risk lasts for at least 25 years after diagnosis, suggesting longer term monitoring is needed Women who are diagnosed with ductal carcinoma in situ (DCIS) outside the NHS breast screening programme are around four times as likely to develop invasive breast cancer and to die from breast cancer than ...
Could kickstart new generation of screening tests for early cancer detection, say researchers A sex-specific panel of 10 proteins can pick up 18 different early stage cancers, representing all the major organs of the human body, finds a proof of concept study published in the open access journal BMJ Oncology. The ...
Absolute risk of cervical cancer remains low, but results show importance of regular checks for women having active surveillance Actively monitoring abnormal cells (lesions) that line the cervix rather than removing them straight away is associated with an increased long term risk of cervical cancer, suggests a study published by The ...
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