Investigation finds evidence of serious misreporting, raising fresh doubts over the approval and decade long use of ticagrelor In a follow up investigation into the multibillion dollar drug ticagrelor, The BMJ has uncovered fresh concerns, this time in key platelet studies used in its FDA approval. For more than a decade, ticagrelor ...
More individuals are seeking treatment for ketamine addiction Greater awareness, research, and treatments are needed The rise in non-prescribed ketamine use across the UK in recent years is a cause for concern, say doctors in The BMJ today. Irene Guerrini at South London & Maudsley NHS Foundation Trust and colleagues warn that ...
Findings support use of P2Y12 therapy instead of aspirin for long term prevention Giving a P2Y12 inhibitor anti-clotting drug to patients with coronary artery disease is associated with lower rates of cardiovascular death, heart attack and stroke compared with traditional aspirin, with no increased risk of major bleeding, finds a ...
Results support the potential for dapagliflozin to benefit these patients The sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin, widely used to treat type 2 diabetes, also shows improvements for patients with progressive liver disease, finds a clinical trial from China published by The BMJ today. The results show that treatment with ...
Findings support broader clinical adoption of no-touch technique to enhance long term patient health ‘No-touch’ vein harvesting significantly reduces the risk of graft failure up to three years after coronary artery bypass surgery compared with conventionally harvested vein grafts, finds a study from China published by The BMJ today. The no-touch technique ...
But findings highlight need for close monitoring of patients throughout their treatment journey, say researchers Treatment with gabapentinoids - drugs such as gabapentin and pregabalin - is not directly associated with an increased risk of self-harm, finds a UK study published by The BMJ today. However, rates of self-harm were higher before ...
Better suppresses usual nocturnal worsening of asthma than dosing at other times May lead to better outcomes without increasing steroid-related side effects or costs A single daily preventer dose of inhaled corticosteroid (beclomethasone), taken mid afternoon, may be the best timing for effective asthma control as it suppresses the usual ...
Premenstrual syndrome (PMS) symptoms eased after taking open-label placebos and women had no substantial side effects Women affected by premenstrual syndrome (PMS) appear to experience less intense and debilitating symptoms after taking placebo pills even when told they do not contain any active medication, suggests a study published in the ...
Technique has the potential to improve care for patients with carotid disease, say researchers Using ultrasound during surgery to unblock carotid arteries is a safe and effective way to significantly reduce the risk of stroke and death, finds a trial published by The BMJ today. The technique, called sonolysis, uses continuous ultrasound ...
And pain relief only marginally better than placebo, pooled data analysis shows Only around 1 in 10 common non-surgical and non-invasive treatments for lower back pain is effective, suggests a pooled data analysis of the available research, published online in BMJ Evidence Based Medicine. And the pain relief they offer is ...