But findings highlight need for close monitoring of patients throughout their treatment journey, say researchers Treatment with gabapentinoids - drugs such as gabapentin and pregabalin - is not directly associated with an increased risk of self-harm, finds a UK study published by The BMJ today. However, rates of self-harm were higher before ...
Better suppresses usual nocturnal worsening of asthma than dosing at other times May lead to better outcomes without increasing steroid-related side effects or costs A single daily preventer dose of inhaled corticosteroid (beclomethasone), taken mid afternoon, may be the best timing for effective asthma control as it suppresses the usual ...
Premenstrual syndrome (PMS) symptoms eased after taking open-label placebos and women had no substantial side effects Women affected by premenstrual syndrome (PMS) appear to experience less intense and debilitating symptoms after taking placebo pills even when told they do not contain any active medication, suggests a study published in the ...
Technique has the potential to improve care for patients with carotid disease, say researchers Using ultrasound during surgery to unblock carotid arteries is a safe and effective way to significantly reduce the risk of stroke and death, finds a trial published by The BMJ today. The technique, called sonolysis, uses continuous ultrasound ...
And pain relief only marginally better than placebo, pooled data analysis shows Only around 1 in 10 common non-surgical and non-invasive treatments for lower back pain is effective, suggests a pooled data analysis of the available research, published online in BMJ Evidence Based Medicine. And the pain relief they offer is ...
Despite previous concerns, findings provide reassurance about the psychiatric safety of these drugs, say researchers Use of GLP-1 receptor agonists to treat type 2 diabetes is not associated with an increased risk of suicidality compared with two other groups of diabetes drugs known as DPP-4 inhibitors and SGLT-2 inhibitors, finds ...
Findings highlight need to reassess intraoperative pain relief strategies, say researchers The use of powerful synthetic opioids, such as sufentanil and remifentanil, during surgery is linked to a subsequent poor ‘pain experience’---a composite of emotional, cognitive, and physical aspects of pain— suggests research published in the open access journal Regional Anesthesia ...
Larger studies of varying doses and longer term effects now warranted, say researchers Melatonin supplementation may help offset the DNA damage associated with night shift work by boosting the body’s ability to repair it, suggest the findings of a small clinical trial published online in the journal Occupational & Environmental Medicine. ...
Commonly used injections offer little or no pain relief, says expert panel Findings question whether it’s reasonable to continue to offer these procedures outside of clinical trials Spine injections should not be given to adults with chronic back pain because they provide little or no pain relief compared with ...
Platinum based drugs, taxanes, and lung cancer associated with highest pain prevalence Worldwide, cancer chemotherapy is linked to persistent severe peripheral nerve pain (neuropathy) for around 4 in every 10 patients treated with these drugs, suggests a pooled data analysis of the available evidence, published in the open access journal Regional ...
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