Despite previous concerns, findings provide reassurance about the psychiatric safety of these drugs, say researchers Use of GLP-1 receptor agonists to treat type 2 diabetes is not associated with an increased risk of suicidality compared with two other groups of diabetes drugs known as DPP-4 inhibitors and SGLT-2 inhibitors, finds ...
Findings highlight need to reassess intraoperative pain relief strategies, say researchers The use of powerful synthetic opioids, such as sufentanil and remifentanil, during surgery is linked to a subsequent poor ‘pain experience’---a composite of emotional, cognitive, and physical aspects of pain— suggests research published in the open access journal Regional Anesthesia ...
Larger studies of varying doses and longer term effects now warranted, say researchers Melatonin supplementation may help offset the DNA damage associated with night shift work by boosting the body’s ability to repair it, suggest the findings of a small clinical trial published online in the journal Occupational & Environmental Medicine. ...
Commonly used injections offer little or no pain relief, says expert panel Findings question whether it’s reasonable to continue to offer these procedures outside of clinical trials Spine injections should not be given to adults with chronic back pain because they provide little or no pain relief compared with ...
Platinum based drugs, taxanes, and lung cancer associated with highest pain prevalence Worldwide, cancer chemotherapy is linked to persistent severe peripheral nerve pain (neuropathy) for around 4 in every 10 patients treated with these drugs, suggests a pooled data analysis of the available evidence, published in the open access journal Regional ...
Results show potentially meaningful effects, but are generally of low certainty Actively preparing for major surgery by exercising and improving diet (known as “prehabilitation”) is associated with fewer complications, less time in hospital, and improved recovery and quality of life in adults, finds an analysis of clinical trials published by The ...
Study provides a practical strategy to achieve remission for adults with type 2 diabetes Adults with overweight or obesity and type 2 diabetes who are given the sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin alongside moderate calorie restriction achieve much higher rates of remission compared with calorie restriction alone, ...
Combined with age and sex, predictive power as good as that of traditional risk factors alone Practical, easily implementable approach for primary healthcare and low-resource settings A vascular ‘fingerprint’ on the light sensitive tissue layer at the back of the eye—the retina—can predict a person’s risk of stroke as accurately ...
Survival ranges from 9 years at age 60 for women to 2 years at age 85 for men But predicting need for nursing home care remains complex The average life expectancy of people diagnosed with dementia ranges from 9 years at age 60 to 4.5 years at age 85 for ...
But are also more likely to swear during the task Surgeons are quicker and more successful at completing a buzz wire game compared with other hospital staff, finds a study in the Christmas issue of The BMJ. However, surgeons are also more likely to swear during the task, while nurses and ...