Approval mechanisms must be grounded in patient need and population health A new UK drug approval pathway, designed to speed up the availability of new medicines, benefits industry over patients and the NHS, argues an expert in The BMJ today. The pathway aligns regulatory review by the Medicines and Healthcare products Regulatory ...
New trial adds high quality evidence on benefits of tranexamic acid for high-risk women Giving tranexamic acid to women with placenta praevia (when the placenta covers the cervical opening) undergoing caesarean birth leads to a significant yet modest reduction in severe bleeding after delivery with no evidence of an increase in ...
Findings align with existing safety data, supporting continued use of aluminium-adjuvanted vaccines in immunisation programmes. Current evidence does not support direct (causal) associations between aluminium adjuvanted vaccines and serious or long term health outcomes, including autism, diabetes and asthma, finds a review of the latest data published by The BMJ today. Small ...
Findings offer reassurance to clinicians and pregnant women, say researchers A large South Korean study published by The BMJ today finds no increased risk of psychiatric or neurodevelopmental disorders, such as ADHD and autism, in children whose mothers used sedative drugs (benzodiazepines or Z-hypnotics) during pregnancy. Benzodiazepines and Z-hypnotics are used to ...
Accelerated continuous theta burst stimulation (a-cTBS) may be a “viable and scalable therapeutic option” say researchers A new non-invasive brain stimulation technique known as accelerated continuous theta burst stimulation (a-cTBS) improves social communication at one month follow up and has a favourable safety profile in children with autism, finds a ...
As the oldest person elected president of the United States, Donald Trump has long faced questions about his health. But is it appropriate for doctors to comment publicly on a president’s mental health? In an opinion article published by The BMJ today, David Nicholl and Trisha Greenhalgh examine the ethical ...
Extreme A&E waits causing patient harm, say experts, with some saying they’d rather die at home Exclusive data published by The BMJ today show that 13,386 patients in England waited at least three days for A&E treatment last year, part of almost 500,000 who spent over 24 hours stuck in ...
Findings lend support to the lasting impact of improving early life conditions A large Swedish study published in The BMJ today suggests that an improved early home environment can have lasting positive effects across generations. Children of parents with psychiatric or behavioural issues who were adopted before age 10 into ...
The UK’s renewed Women’s Health Strategy, announced by the Department of Health and Social Care, NHS England and Wes Streeting, signals a shift from listening to action, with women’s voices more directly shaping how care is designed and improved. There is a clear focus on faster diagnosis, more joined-up ...
Investigation explores how an $80,000 a year drug was approved for primary progressive form of MS despite concerns over its safety and effectiveness The US Food and Drug Administration (FDA) is reviewing a petition to revoke the approval of Roche’s top-selling drug ocrelizumab (Ocrevus) for treating primary progressive multiple sclerosis ...
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